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Table 4 Global Cognition and Mismatch Negativity (MMN) Amplitude z-scores for Participants With Schizophrenia Who Received Computerized Auditory Training and Participants Who Played Computer Games

From: Trait aspects of auditory mismatch negativity predict response to auditory training in individuals with early illness schizophrenia

 

Auditory Training (n = 27)

Computer Games (n = 29)

Baseline

Post

Baseline

Post

 

Outcome Measureb

Mean

SD

Mean

SD

Mean

SD

Mean

SD

Fa

p-value

Effect Size

Global Cognition

−1.12

0.93

−0.87

0.98

−0.96

0.85

−0.95

0.94

2.96

0.09

0.25

DBL MMNc

0.35

0.99

0.46

0.81

0.44

0.88

0.38

0.89

0.60

0.44

0.18

DUR MMNc

0.34

0.92

0.28

0.73

0.19

1.02

0.34

0.85

0.89

0.35

-0.23

FREQ MMNc

0.32

1.00

0.45

1.10

0.43

0.99

0.10

1.02

4.83

0.03

0.46

  1. FREQ Frequency Deviant, DUR Duration Deviant, DBL Frequency + Duration Double-Deviant
  2. MATRICS Measurement and Treatment Research to Improve Cognition in Schizophrenia
  3. a Repeated measures ANOVA, Treatment Group x Time interaction
  4. b Cognitive measures were transformed to z-scores using normative data of healthy samples. Global Cognition is the average z-score across all measures from the MATRICS
  5. c Group mean and standard deviation (SD) mismatch negativity (MMN) age-corrected z-scores for each deviant type averaged over the six fronto-central leads (F3, Fz, F4, C3, Cz, C4)
  6. Statistically significant p-values are formatted in bold