|
SZ (n=40)
|
HC (n=12)
| | |
---|
Variable
|
Mean
|
(SD)
|
Mean
|
(SD)
|
T-score (df=50)
|
p-valueb
|
---|
Age
|
46.10
|
12.41
|
43.33
|
13.22
|
0.67
|
0.510
|
Age of Onset
|
20.84
|
6.70
|
-
|
-
| | |
Hospitalizations (#)
|
13.77
|
25.08
|
-
|
-
| | |
PANSS total
|
56.87
|
13.22
|
-
|
-
| | |
Positive
|
16.20
|
5.80
|
-
|
-
| | |
Negative
|
13.07
|
4.78
|
-
|
-
| | |
General
|
27.60
|
7.18
|
-
|
-
| | |
Antipsychotic CPZ Eq
|
578.81
|
404.73
|
-
|
-
| | |
Antipsychotic Any
|
37 of 40
|
-
|
-
|
-
| | |
Traditional only
|
9 of 37
|
-
|
-
|
-
| | |
Atypical only
|
25 of 37
|
-
|
-
|
-
| | |
SWMT total
|
63.33
|
11.02
|
75.58
|
7.62
|
3.59
|
0.001
|
WTAR FSIQ
|
91.45
|
13.98
|
100.73
|
15.82
|
1.90
|
0.064
|
CPT-IPa
|
38.03
|
11.61
|
42.75
|
11.66
|
1.24
|
0.220
|
MCCB WM Compositea
|
37.18
|
10.80
|
46.67
|
8.99
|
2.77
|
0.008
|
|
%
| |
%
| |
c2 (df=1)
|
p-valueb
|
Gender (Male)
|
57.50
|
-
|
50.00
|
-
|
0.21
|
0.646
|
Race (Caucasian)
|
35.00
|
-
|
58.00
|
-
|
1.23
|
0.267
|
Handedness (Right)
|
85.00
|
-
|
100.00
|
-
|
2.04
|
0.362
|
- PANSS: Positive and Negative Syndrome Scale, CPZ Eq: chlorpromazine equivalent, SWMT: Sternberg Working Memory Task, WTAR: Wechsler Test of Adult Reading, CPT-IP: Continuous Performance Test-Identical Pairs, MCCB: MATRICS Cognitive Composite Battery
-
a Age, education, and gender corrected t-scores reported according to MCCB normative sample
-
b Statistic reported based on two-tailed test