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Table 2 RCTs of tDCS and CCT for depressed patients

From: Application of transcranial direct current stimulation to psychiatric disorders: trends and perspectives

Author, Year N Arms tDCS protocol Results
Segrave, 2014 (Segrave et al. 2014) 27 CCT + tDCS 5 sessions in one week, Significantly more change in MADRS and BDI-II over time in CCT + tDCS than others
Sham CCT + tDCS 2 mA, 24 min, 35 cm2
CCT + sham tDCS A/C: F3/F8
Brunoni, 2014 (Brunoni et al. 2014) 37 CCT + tDCS CCT + sham tDCS 10 sessions in two weeks, 2 mA, 30 min, 25 cm2 Anode: F3
Cathode: F4
Both groups show recovery after four weeks and non-significantly larger improvement of HDRS and BDI in CCT + sham tDCS
Vanderhasselt, 2015 (Vanderhasselt et al. 2015) 33 CCT + tDCS CCT + sham tDCS 10 sessions in two weeks, 2 mA, 30 min, 25 cm2Anode: F3 Cathode: F4 No significant difference in terms of HDRS and BDI
  1. CCT: cognitive control training, tDCS: transcranial direct current stimulation, A/C: placement of anode/cathode electrodes, MADRS: Montgomery–Åsberg Depression Rating Scale, BDI: Beck depression inventory, HDRS: Hamilton Depression Rating Score
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