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Table 1 Psychiatric neuromodulation methods compared with tDCS (adapted from (George et al. 2011))

From: Application of transcranial direct current stimulation to psychiatric disorders: trends and perspectives

 

ECT

VNS

TMS

DBS

tDCS

Clinical Approval By FDA

Depression

Epilepsy

TRD

PD

None approved

Schizophrenia etc.

TRD

Migraine

TRD

   

OCD

Anesthesia

General

General

No

General

No

Possible Risks

Amnesia

Hoarseness

Headache

Stroke

Skin redness

Delirium

Cough

Dizziness

Infection

Scalp discomfort

  

Scalp discomfort

Seizure

 

Number of sessions for depression

8 to 12 sessions

NA

20 to 30 sessions

NA

5 to 15 sessions

2 to 3 sessions a week

 

3–5 sessions a week

 

3–5 sessions a week

General cost in the U.S.

$800 to $1000 per session

$5,000 to $30,000

$300 per session

$130,000 (Stroupe et al. 2014)

No more than TMS per session

  1. ECT: electroconvulsive therapy, VNS: vagus nerve stimulation, TMS: transcranial magnetic stimulation, tDCS: transcranial direct current stimulation, TRD: treatment-resistant depression, PD: Parkinson’s disease, OCD: Obsessive-compulsive disorder, NA: not applicable