TY - JOUR AU - Knott, Verner AU - Impey, Danielle AU - Choueiry, Joelle AU - Smith, Dylan AU - de la Salle, Sara AU - Saghir, Salman AU - Smith, Meaghan AU - Beaudry, Elise AU - Ilivitsky, Vadim AU - Labelle, Alain PY - 2015 DA - 2015/05/06 TI - An acute dose, randomized trial of the effects of CDP-Choline on Mismatch Negativity (MMN) in healthy volunteers stratified by deviance detection level JO - Neuropsychiatric Electrophysiology SP - 1 VL - 1 IS - 1 AB - Alpha 7 nicotinic acetylcholine receptors (α7 nAChR) are prioritized molecular targets for the development of new pharmacological treatments for impaired cognition in schizophrenia. The use of schizophrenia-associated biomarkers both as endpoints and for segmentation of homogeneous populations for early detection of cognitive enhancing agents has been advanced to enhance the drug discovery process. SN - 2055-4788 UR - https://doi.org/10.1186/s40810-014-0002-4 DO - 10.1186/s40810-014-0002-4 ID - Knott2015 ER -