| Auditory Training (n = 27) | Computer Games (n = 29) |
---|
Baseline | Post | Baseline | Post | Â |
---|
Outcome Measureb
| Mean | SD | Mean | SD | Mean | SD | Mean | SD | Fa
|
p-value | Effect Size |
---|
Global Cognition | −1.12 | 0.93 | −0.87 | 0.98 | −0.96 | 0.85 | −0.95 | 0.94 | 2.96 | 0.09 | 0.25 |
DBL MMNc
| 0.35 | 0.99 | 0.46 | 0.81 | 0.44 | 0.88 | 0.38 | 0.89 | 0.60 | 0.44 | 0.18 |
DUR MMNc
| 0.34 | 0.92 | 0.28 | 0.73 | 0.19 | 1.02 | 0.34 | 0.85 | 0.89 | 0.35 | -0.23 |
FREQ MMNc
| 0.32 | 1.00 | 0.45 | 1.10 | 0.43 | 0.99 | 0.10 | 1.02 | 4.83 |
0.03
| 0.46 |
-
FREQ Frequency Deviant, DUR Duration Deviant, DBL Frequency + Duration Double-Deviant
-
MATRICS Measurement and Treatment Research to Improve Cognition in Schizophrenia
-
a Repeated measures ANOVA, Treatment Group x Time interaction
-
b Cognitive measures were transformed to z-scores using normative data of healthy samples. Global Cognition is the average z-score across all measures from the MATRICS
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c Group mean and standard deviation (SD) mismatch negativity (MMN) age-corrected z-scores for each deviant type averaged over the six fronto-central leads (F3, Fz, F4, C3, Cz, C4)
- Statistically significant p-values are formatted in bold